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Issue DateTitleAuthor(s)
2014-09Phenolic and flavonoid contents and anti-oxidative potential of epicarp and mesocarp of Lagenaria siceraria fruit: a comparative studyAhmad, Dr. Dildar; Saeed, Sana; Fatima, Munim
2015Bioactive compounds from Carissa opaca roots and xanthine oxidase and alpha-amylase inhibitory activities of their methanolic extract and its fractions in different solventsAhmad, Dr. Dildar; Saeed, Ramsha
2014-10-20Analysis of Phenolic and Flavonoid Contents, and the Anti-Oxidative Potential and Lipid Peroxidation Inhibitory Activity of Methanolic Extract of Carissa opaca Roots and Its Fractions in Different SolventsAhmad, Dr. Dildar; Saeed, Ramsha; Khaizran, Fatima
2016Carissa opaca: A plant with great potential for future drugs for degenerative and infectious diseasesIzhar, Sania; Ahmad, Dr. Dildar
2014-08-17The objective of the present work was to investigate the anti-oxidative potential of methanolic extract of Carissa opaca roots and its fractions in solvents of different polarities. Total phenolic (TPC) and flavonoid (TFC) contents of methanolic extract were 211.95 ± 0.78 μg/mL gallic acid equivalents (GAE) and 8.35 ± 0.21 μg/mL rutin equivalents (RE), respectively. Ethyl acetate contained the highest amounts of both (TFC, 11.8 ± 0.28 RE; TPC, 342.80 ± 0.42 GAE) followed by chloroform fraction (TFC, 7.50 ± 0.14 RE; TPC, 275.85 ± 0.50 GAE). Extract and fractions displayed remarkable DPPH radical scavenging activity. EC50 values of methanolic extract was 0.88 mg/mL, while that of hexane, chloroform, ethyl acetate, n-butanolic and aqueous fractions were 0.58, 0.38, 0.29, 0.36 and 5.83 mg/mL, respectively, ethyl acetate fraction being most potent. The ethyl acetate fraction also showed the highest activity in terms of reducing power, phosphomolybdate and ABTS assays. All the fractions showed fairly good lipid peroxidation inhibitory activity, which remained almost constant over three days. Based on the results it can be concluded that roots of Carissa opaca contains phytochemicals with exploitable antioxidant, free radical scavenging, and lipid peroxidation inhibitory potential.Chaudhery, Raza; Ahmad, Dr. Dildar; Parsa, Dar; Liaqat, Inam; shaban, Muhammad
2016Synthesis of Schiff bases of acetophenone with aniline and its different chloro-substituted derivatives, and study of their antioxidant, anti-enzymatic and antimicrobial propertiesMir, Hira; Ahmad, Dr. Dildar
2017Phase behavior of a TX-100/oleic acid/water based ternary system: A microstructure studyRahman, H. M.A; Afzal, S.; Nazar, M. F.; Ahmad, Dr. Dildar; Khan, A. M.; Asghar, Muhammad N.
2018The assay-guided isolation of chemical constituents from a medicinal plant (Carissa opaca), and the study of their bio activities.Ahmad, Dr. Dildar
2016Synthesis of novel sulfonamide derivatives as inhibitors of ectonucleotidasesAhmad, Dr. Dildar; Rashida, Dr. Mariya A.
2015Isolation and identification of bioactive compounds from chloroform fraction of methanolic extract of Carissa opaca rootsMasih, Rashid; Saeed, Ramsha; Fatima, Khairzan; Ahmad, Dr. Dildar